Thứ Bảy, 1 tháng 9, 2018

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Welcome to another episode of Behind the Science:

on Location.

I'm your host, Jennifer Fornier.

In my neighborhood, we have an active responder program,

volunteers who are trained in emergency preparedness skills

to help save lives.

What if we can be more proactive here and incorporate

natural, active responders to our diet?

What am I talking about?

Well, when you're looking for clinically relevant compounds

that are biologically active, these

are natural physiological active responders

that could help us avoid life-threatening situations.

In this episode of Behind the Science,

let's take a trip to a lab at the University of Alabama

to see what makes a difference between a non-responder

and an active responder.

Hi, Kristi.

Hi, welcome back.

Thanks for having me.

I was so intrigued the last time I was here with the work

that you were doing in regards to the active and non-active

responders, especially related to oxidative stress

for high fat diets.

Could you tell me a little bit more

about the work that you're doing?

Sure, actually, my Redox lab investigates

bioactive compounds that reduce oxidative stress.

And it protects cardiovascular health.

But we've been using the mass spec

to analyze lycopene in serum of rats

that were diet-induced obesity.

Our hypothesis with this is that if you have a high fat diet,

it induces a level of oxidative stress above baseline.

But then also you're accruing adipose tissue.

So a double negative of oxidative stress.

So our question is, can lycopene added to a high fat diet

reduce this oxidative stress that's

coming from both the diet and the accrual of adipose tissue.

Rather than me sharing the results with you,

let me introduce you to my doctoral student, Katelyn.

This is her body of research.

Hey.

Hi, Katelyn.

Nice to meet you.

Nice to meet you, too.

My guess is that you've been working on this for a long time

and that you have a lot of data associated with it.

That's true.

Let me take you to the white board.

It'd be a great place to show you.

Let's take a look.

So we decided to look at lycopene's influence

in Sprague-Dawley rats fed diets meeting and exceeding

recommendations for fat intake in humans.

So what I mean by this is that our control group

was fed a 30% fat purified diet, with 100 milligrams of lycopene

per day.

Whereas our treatment group consumed 60% fat

purified diet with 100 milligrams of lycopene per day.

So what you see in the first graph

is that there's a continuous increase

in adipose tissue for the rats fed the 60% fat diet.

So what you think is that they'd have

significantly greater levels of oxidative stress 10 weeks out.

But what we see is that although they do have a greater level,

it's not significant.

So what does that bring us to?

Lycopene may assist in attenuating

the oxidative stress that's induced by a high fat diet.

But we only observed this through 10 weeks,

so the long-term accrual of adipose tissue

may actually surpass lycopene's ability

to exert that protective effect.

Well, that was very impressive data.

It looks like lycopene is an effective active responder.

It certainly is an effective active responder

to oxidative stress.

We're excited for our next steps to look at serum lycopene

to see if it's more heavily deposited in the adipose tissue

of the rats fed the high fat diet.

So, since you're here and you're wearing a lab coat,

do you want to come run some samples to differentiate

between responders and non-responders?

I'd love to.

Let's get to work.

Sounds great.

Nature is amazing.

How cool is it that there are compounds such as lycopene

found in many fruits and vegetables that

can serve as active responders to help reduce oxidative stress

and protect our cardiovascular health?

It's also important to understand

how other factors, such as a high fat diet,

would increase or decrease this active responder's ability

to be beneficial.

If you'd like to learn more about the great work being done

in Dr. Kristi Crowe-White's Redox lab,

check out the link below.

And join us next time for another episode of

Behind the Science: On Location.

For more infomation >> Looking for active responders to oxidative stress at the University of Alabama - Duration: 3:59.

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Kal Ho Na Ho | Havas Guruhi | Monad University | Practice | PR Music - Duration: 4:56.

https://www.youtube.com/watch?v=RDsV6mLKqc4

https://www.youtube.com/watch?v=raxenUvZczQ

https://www.youtube.com/watch?v=7tEJ3Y6fAgQ

https://www.youtube.com/watch?v=Xqzs7iR8JGk

https://www.youtube.com/watch?v=aWU6IJe4q64

https://www.youtube.com/watch?v=wE2osAo133Q

https://www.youtube.com/watch?v=vEVtQOZpoys

https://www.youtube.com/watch?v=-H6FuCbiUjQ

For more infomation >> Kal Ho Na Ho | Havas Guruhi | Monad University | Practice | PR Music - Duration: 4:56.

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2018 New Student Orientation | Idaho State University - Duration: 3:04.

Hello! I'm from Aberdeen, Idaho.

I'm Kenny Young and I'm from Blackfoot, Idaho.

I'm Dreya Joseph and I'm from Pocatello.

My name is Brandon Queen. I'm here from Japan.

What brings me to Idaho State University is that it's such a great campus and I got scholarships here

and going into Political Science and Spanish, it gave me a program that I could follow.

A university that's close to home and so I could study biomedical sciences.

Mechanical engineering and my son's here in Idaho.

Affordability and they have a really good clinical psych program.

Hi, I'm Alyssa Desmit, I'm from North Carolina

I'm from Maridian Idaho.

My name is Ashley and I'm from Twin Falls.

Bryce Turner and I'm from Bear Lake Idaho.

I just want to get away from family a little bit maybe and study the biology program here.

I am on an athletic scholarship for track and I am studying physical therapy.

I'm here on academic scholarships and I am studying Spanish for Health Professions.

The geology department and the close proximity to the outdoors and hiking.

For more infomation >> 2018 New Student Orientation | Idaho State University - Duration: 3:04.

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2018 Auburn University NCAA Commercial Participant - Heather Bain - Duration: 1:28.

My name's Heather Bain, I'm a town operations manager for Amazon Web Services.

And, I manage a team of recruiting coordinators and they are pretty much in charge of the

candidate experience for all of our candidates that are interviewing with Amazon Web Services.

I spent 8 years as an Army officer and as I was getting out and looking at various roles

to get into, uh Amazon really peaked my interest.

They're obviously doing a lot of really amazing things, um in a lot of different spaces and

so to get the opport-, opportunity to work at AWS and kind of be the louder in cloud

uh technology was really appealing.

And then this role actually gave me the opportunity to still manage people, and that was something

that was really important to me coming out of the Army, was to have the ability to kind

of still influence lives um and be in a leadership role.

My experience at Auburn really helped me achieve success by laying a foundation of hard work,

um, and then the Auburn family is obviously a very real thing.

And, the network out there is just phenomenal and you can really kind of lean in whenever

you need help along the way and kind of any Auburn grad that you find really takes you

in and is willing to help you uh achieve success in your career.

It's really one of the most welcoming and warming places you could ever go to.

Um, no matter how long it's been since you've been at Auburn, as soon as you go back you

immediately feel like you're at home.

For more infomation >> 2018 Auburn University NCAA Commercial Participant - Heather Bain - Duration: 1:28.

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Building a global university - Duration: 1:42.

[MUSIC PLAYING]

I don't think there are many global universities yet.

Heriot-Watt is starting on that journey

as being a global institution.

A global university moves on from being just one that's

got branch campuses.

The difference is that our campuses are

in different countries, but they could

be like an institution that's got three or four campuses

down the road from each other.

Going global at Heriot-Watt means

that the student can start on one campus,

enroll in a program, and for one the years

of their degree take the same program

at another of our campuses.

It was an ambition of our Malaysia campus to start with.

It's a great recruitment tool for us.

It's really started to take off, and has actually

grown now so that we've got, this year, over 500 students

studying on a different campus.

The applications for next academic year

just started, and we've already got 700 applications.

We have to understand that how you recruit and apply

to be an applicant in Malaysia, or Dubai,

or the UK are all very different from each other.

And so when we were looking for a new admissions system,

we were really keen to find one that

could be adapted to cope with different needs

in different countries, but still

meet the Heriot-Watt need of actually having

simple standard processes that were effective

and enable us to manage our data in a far better way

than we were able to before.

[MUSIC PLAYING]

For more infomation >> Building a global university - Duration: 1:42.

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2018 Auburn University NCAA Commercial Participant - Ashley Robinson - Duration: 1:40.

Here at Under Armour I work for the IT Business Partners team and I initially became interested

in this role because I actually interned with Under Armour for two summers prior to becoming

a full time teammate.

And I was able to work on the same team and really able to learn a lot about it and I

fell in love with it.

So my day-to-day um a lot includes, includes a lot of meeting with the stakeholders of

various departments from accounting to product to marketing.

It's an interesting job because I get to work with a lot of different areas throughout

the business.

my Auburn degree has helped me to achieve success especially here at Under Armour because

the foundation that they provided was really rock solid.

The business school provided a really good curriculum as far as being able to touch all

areas of IT and really getting a feel for what the different options are when they go

into the workforce.

I came from a really small high school outside of state so I didn't really know a lot of

people coming in but I still wanted a kind of a big school feel.

And it was a really easy transition for me coming from outside, from another state and

from a small school coming to Auburn because it still had that small feel, and family feel,

and it just felt more like home.

Some advice I would have for students considering attending Auburn, I would suggest when you

go to tour campus, make sure you're touring the individual colleges as well.

So take a look at the business school, the engineering school, the liberal arts school.

And then when you become a freshman, make sure you're using your electives to explore

areas outside of what your major is because there may be opportunities that you weren't

originally thinking about.

For more infomation >> 2018 Auburn University NCAA Commercial Participant - Ashley Robinson - Duration: 1:40.

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Take a look inside Prince Harry's university dorm as Halle Berry spots a picture of herself in his E - Duration: 2:32.

 A photo of Prince Harry's Eton College dormitory room is being shared across the internet for a hilarious reason

 Meghan Markle's husband can be seen as a young student, grinning as he poses alongside his textbooks and stereo system in the now-viral photo

However, it's what is posted on the wall behind him that has caught everyone's eye

 Hanging above his desk is a decorative beach throw with an image of Hollywood actress Halle Berry in the middle

 And when the actress caught sight of the photo she made sure to publicly acknowledge it with a hilarious caption

Top Stories The Queen has a very UNUSUAL hobby – and it is not horses or corgis Prince Harry SINGS on stage after watching Hamilton with wife Meghan Markle  Referencing a Missy Elliot lyric, "don't I look like a Halle Berry poster?", she wrote: "Ok #PrinceHarry, I see you! #HalleBerryPosta @MissyElliott

"  But what else did Prince Harry have in his university room? Here, we take a closer look at the young royal's dorm

Tribute to mum Princess Diana  Prince Harry made sure to keep a photo of his mum by his side throughout his time at university

 Proudly displayed on his desk top was a framed picture of Princess Diana. Most Popular Sam Attwater accuses Roxanne Pallett of claiming he'd hit her Celebrity Big Brother 2018's Roxanne Pallett punch: What really happened ER actress Vanessa Marquez shot dead by police after 'pulling a BB gun on officers' Mario Testino book  Photographer Mario Testino has worked with all of the royal family throughout the years, so it's no surprise Harry had one of his books in his collection at uni

 Harry was 19 years old when the photo of his uni room was taken, and at 21 years old he marked the milestone birthday with a series of portraits taken by Mario Testino of himself with brother Prince William and their father Prince Charles

How he proved he's just like any other university student  The sweet snap of Harry also showed he was just like any other young man at university, from the pictures of scantily-clad females on the wall, to the England flag above his chest of drawers – Harry's room undoubtedly looked no different to his classmates'

 There were also cups of coffee, a nineties CD player, and family photos pinned to the wall

Top Stories Meghan Markle tuxedo dress: Duchess of Sussex's short outfit is a Meghan Markle favourite Princess Diana sweatshirt: USA jumper Prince Harry's mother wore before her death up for sale Meghan and Harry's children will not have the same surname as George, Charlotte and Louis

For more infomation >> Take a look inside Prince Harry's university dorm as Halle Berry spots a picture of herself in his E - Duration: 2:32.

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2018 Auburn University NCAA Commercial - Duration: 0:31.

Tim Vines: Let me be the first to lead you in War Eagle as the newest graduates of Auburn University.

Graduates: Warrrrrrrrrrrrrrrrrrrrrrrrr…

Passing Jogger: War Eagle Ashley: War Eagle

(Musician plays War Eagle fight song)

Rob: War Eagle

Driver: War Eagle, Luv. Where to?

Lauren: War Eagle. Heathrow.

Passenger: Hey, War Eagle

Jared: War Eagle

Barista: Macchiato (Shouting)

Heather: War Eagle

Thom Gossom: You never really leave Auburn…

Because Auburn never leaves you.

Graduates: Eagle! Hey!

For more infomation >> 2018 Auburn University NCAA Commercial - Duration: 0:31.

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Types of Girls in a University || O M G tv || Assamese Comedy Video || Dibrugarh University - Duration: 6:10.

Types of Girls in a University (Editor got confused, Sincere apologies)

For more infomation >> Types of Girls in a University || O M G tv || Assamese Comedy Video || Dibrugarh University - Duration: 6:10.

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Large tree crushes vehicle at University area park - Duration: 0:22.

For more infomation >> Large tree crushes vehicle at University area park - Duration: 0:22.

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Ep. 56: University of Louisville asks Adult Students for a Second Chance w/ Dr. Matt Bergman - Duration: 1:55.

For more infomation >> Ep. 56: University of Louisville asks Adult Students for a Second Chance w/ Dr. Matt Bergman - Duration: 1:55.

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Motivational Speech || STEVE JOBS Stanford University speech || English Subtitle - Duration: 14:34.

Thank You

I am honored to be with you today for your commencement from one of the finest universities in the world.

Truth be told, I never graduated from college and this is the closest I've ever got into college graduation.

Today I wanna tell you three stories from my life that's it! No big deal just 3 stories.

The first story is about connecting the dots

I dropped out of REED College after the first 6 months but then stayed around as a drop-in for another 18 months or so before I really quit.

So why did I drop out?

It started before I was born.

My biological mother was a young unwed graduate student, and she decided to put me up for adoption.

She felt very strongly that I should be adopted by college graduates, so everything is all set for me to be adopted by lawyer and his wife.

Except when I popped out they decided at the last minute that they really wanted a girl.

So my parents who were on a waiting list got a call in the middle of the night asking:

we got an unexpected baby boy, do you want him?

They said "of course"

My biological mother found out later that, my mother had never graduated from college and my father had never graduated from high school.

She refused to sign the final adoption papers.

She only relented a few months later when my parents promised that I would go to college. This was the start in my life.

And 17 years later I did go to college but I naively chose a College almost as expensive as Stanford, and all of my working-class parents' saving spent on my college tuition.

After 6 months, I couldn't see the value in it. I had no idea, what I wanted to do with my life and no idea how college was going to help me figure it out.

And here I was spending all the money my parents had saved their entire life.

So I decided to drop-out and trust that it would all work out okay.

IT was pretty scary at the time, but looking back IT was the best decisions I ever made.

The minute I dropped out I could stop taking the required classes that didn't interest me. And begin dropping in on the ones that looked far more interesting.

It wasn't all romantic.

I didn't had a dorm room, so I slept on the floor in friends' rooms, I returned Coke bottles for the 5¢ deposits to buy food with

and I would walk the 7 miles across town every Sunday night to get one good meal a week at the Hare Krishna temple.I loved it.

And much of what I stumbled into by following my curiosity and intuition turned out to be priceless later on. Let me give you one example:

Reed College at that time offered perhaps the best calligraphy instruction in the country.

Throughout the campus every poster, every label on every drawer, was beautifully hand calligraphed.

Because I had dropped out and didn't have to take the normal classes, I decided to take a calligraphy class to learn how to do this.

I learned about serif and sans serif typefaces, about varying the amount of space between different letter combinations, about what makes great typography great.

It was beautiful, historical, artistically subtle in a way that science can't capture, and I found it fascinating.

None of this had even a hope of any practical application in my life.

But 10 years later, when we were designing the first Macintosh computer, it all came back to me.

And we designed it all into the Mac. It was the first computer with beautiful typography.

If I had never dropped in on that single course in college,

the Mac would have never had multiple typefaces or proportionally spaced fonts.

And since Windows just copied the Mac, , it's likely that no personal computer would have them.

If I had never dropped out, I would have never dropped in on this calligraphy class, and personal computers might not have the wonderful typography that they do.

Of course it was impossible to connect the dots looking forward when I was in college. But it was very, very clear looking backward 10 years later.

Again, you can't connect the dots looking forward; you can only connect them looking backwards.

So you have to trust that the dots will somehow connect in your future.

You have to trust in something — your gut, destiny, life, karma, whatever.

Because believing that the dots will connect down the road

It will give you a confidence to follow your heart

Even when it leads you off the well-worn path

And that will make all the difference.

My second story is about love and loss.

I was lucky — I found what I loved to do early in life.

Woz and I started Apple in my parents' garage when I was 20.

We worked hard, and in 10 years Apple had grown from just the two of us in a garage into a $2 billion company with over 4,000 employees.

We had just released our finest creation — the Macintosh — a year earlier, and I had just turned 30.

And then I got fired.

How can you get fired from a company you started?

Well, as Apple grew we hired someone who I thought was very talented to run the company with me,

and for the first year or so things went well.

But then our visions of the future began to diverge and eventually we had a falling out.

When we did, our Board of Directors sided with him. So at 30 I was out, and very publicly out.

What had been the focus of my entire adult life was gone, and it was devastating.

I really didn't know what to do for a few months. I felt that I had let the previous generation of entrepreneurs down

that I had dropped the baton as it was being passed to me.

I met with David Packard and Bob Noyce and tried to apologize for screwing up so badly.

I was a very public failure, and I even thought about running away from the valley.

But something slowly began to dawn on me — I still loved what I did.

The turn of events at Apple had not changed that one bit.

I had been rejected, but I was still in love. And so I decided to start over.

I didn't see it then, but it turned out that getting fired from Apple was the best thing that could have ever happened to me.

The heaviness of being successful was replaced by the lightness of being a beginner again, less sure about everything.

It freed me to enter one of the most creative periods of my life.

During the next five years, I started a company named NeXT, another company named Pixar,

and fell in love with an amazing woman who would become my wife.

Pixar went on to create the world's first computer animated feature film, Toy Story, and is now the most successful animation studio in the world.

In a remarkable turn of events, Apple bought NeXT, I returned to Apple,

and the technology we developed at NeXT is at the heart of Apple's current renaissance.

And Laurene and I have a wonderful family together.

I'm pretty sure none of this would have happened if I hadn't been fired from Apple.

It was awful tasting medicine, but I guess the patient needed it.

Sometimes life hits you in the head with a brick. Don't lose faith.

I'm convinced that the only thing that kept me going was that I loved what I did.

You've got to find what you love, and that is as true for your work as it is for your lovers.

Your work is going to fill a large part of your life, and the only way to be truly satisfied is to do what you believe is great work.

And the only way to do great work is to love what you do. If you haven't found it yet, keep looking. Don't settle.

As with all matters of the heart, you'll know when you find it.

And, like any great relationship, it just gets better and better as the years roll on.

So keep looking until you find it. Don't settle.

My third story is about death.

When I was 17, I read a quote that went something like:

If you live each day as if it was your last, someday you'll most certainly be right.

"It made an impression on me, and since then, for the past 33 years, I have looked in the mirror every morning and asked myself:

"If today were the last day of my life, would I want to do what I am about to do today?"

And whenever the answer has been "No" for too many days in a row, I know I need to change something.

Remembering that I'll be dead soon is the most important tool I've ever encountered to help me make the big choices in life.

Because almost everything — all external expectations, all pride, all fear of embarrassment or failure

these things just fall away in the face of death, leaving only what is truly important.

Remembering that you are going to die is the best way I know to avoid the trap of thinking you have something to lose.

You are already naked. There is no reason not to follow your heart.

About a year ago I was diagnosed with cancer.

I had a scan at 7:30 in the morning, and it clearly showed a tumor on my pancreas.

I didn't even know what a pancreas was.

The doctors told me this was almost certainly a type of cancer that is incurable, and that I should expect to live no longer than three to six months.

My doctor advised me to go home and get my affairs in order, which is doctor's code for prepare to die.

It means to try to tell your kids everything you thought you'd have the next 10 years to tell them in just a few months.

It means to make sure everything is buttoned up so that it will be as easy as possible for your family. It means to say your goodbyes.

I lived with that diagnosis all day.

Later that evening I had a biopsy, where they stuck an endoscope down my throat, through my stomach and into my intestines,

put a needle into my pancreas and got a few cells from the tumor.

I was sedated, but my wife, who was there, told me that when they viewed the cells under a microscope the doctors started crying

because it turned out to be a very rare form of pancreatic cancer that is curable with surgery.

I had the surgery and thankfully, I'm fine now.

This was the closest I've been to facing death, and I hope it's the closest I get for a few more decades.

Having lived through it, I can now say this to you with a bit more certainty than when death was a useful but purely intellectual concept:

No one wants to die.

Even people who want to go to heaven don't want to die to get there.

And yet death is the destination we all share.

No one has ever escaped it, and that is as it should be, because Death is very likely the single best invention of Life.

It is Life's change agent. It clears out the old to make way for the new.

Right now the new is you,

but someday not too long from now, you will gradually become the old and be cleared away.

Sorry to be so dramatic, but it is quite true.

Your time is limited, so don't waste it living someone else's life.

Don't be trapped by dogma — which is living with the results of other people's thinking.

Don't let the noise of others' opinions drown out your own inner voice.

And most important, have the courage to follow your heart and intuition.

They somehow already know what you truly want to become. Everything else is secondary.

When I was young, there was an amazing publication called "The Whole Earth Catalog", which was one of the bibles of my generation.

It was created by a fellow named Stewart Brand not far from here in Menlo Park, and he brought it to life with his poetic touch.

This was in the late 1960s, before personal computers and desktop publishing, so it was all made with typewriters, scissors and Polaroid cameras.

It was sort of like Google in paperback form, 35 years before Google came along

It was idealistic, and overflowing with neat tools and great notions.

Stewart and his team put out several issues of The Whole Earth Catalog, and then when it had run its course, they put out a final issue.

It was the mid-1970s, and I was your age.

On the back cover of their final issue was a photograph of an early morning country road,

the kind you might find yourself hitchhiking on if you were so adventurous.

Beneath it were the words: "Stay Hungry. Stay Foolish."

It was their farewell message as they signed off. Stay Hungry. Stay Foolish.

And I have always wished that for myself. And now, as you graduate to begin a new, I wish that for you.

Stay Hungry. Stay Foolish.

Thank you all very much.

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